Vitamin C is one of the most powerful antioxidants in nature that is dermatologically used to treat and prevent premature aging and hyper-pigmentation. Human beings lack the enzyme which is present in most of the plants and animals that is able to synthesize vitamin C. Therefore the only way we can benefit from this superb antioxidant is the direct application on the skin of a serum containing 20% concentration of Vitamin C or through oral assumption however in the latter way, the benefits for the skin are much less as most of it is metabolized or broken down before reaching the skin.
L-ascorbic acid or simply vitamin C is quite an unstable molecule when exposed to light and oxygen. Because of its inherently unstable form in a natural state, Kleem Organics has adopted the innovative Stay-C 50 (one of the most stable, bio-available forms of vitamin C) which is highly stabilised by the natural esterification of the molecule, in order to provide maximum benefits from the normal vitamin C. Esterification refers to a process wherein an ester (a natural molecule found in plants) is added to the Vitamin C to render it more stable and less prone to react to light and environmental oxygen, hence keeping it fresher and prevents it from expiring for much longer. Moreover in the product formulation, the scientists have been particularly careful in maintaining a pH less than 3.5 for the best protection of the serum, something that seems to be very often underestimated in many other vitamin C serums.

Stay-C 50 vitamin C reduces the formation of free radicals and stimulates the collagen production, helping to improve the overall appearance of the skin, lessening the photo damage and dark spots due to the UV rays, which account for 80% of skin aging, including wrinkles.


The exposure of the skin to the Sun generates highly unstable molecules in the skin cells that modify the structure of the cell and degrading the DNA molecule, the cell membrane and cellular proteins, including collagen. These unstable molecules are called Free Radicals. Every molecule is made of a number of atoms. Each atom has a nucleus at its core which has a positive charge. Orbiting around the nucleus are a number of electrons (negatively charged) to balance out the atom. Free radicals are atoms or molecules which do not possess enough electrons to balance out the electrical charge of the molecule, so the molecule itself becomes highly unstable and reactive, also known as free radical. The only way these unstable molecules, or free radicals can become stable is by stealing electrons from the healthy skin cells, but in doing so they cause everlasting damage to the skin tissue which is seen as typical signs of aging such as blemishes and imperfections in the skin. These free radicals could be caused by various factors, including pollution such as smoke, including that of cigarettes, and UV rays from the sun.
Vitamin C works against this harmful chain of reactions that occurs inside the skin by protecting the skin from the free radicals by donating one of its electrons to the unstable molecule or free radical. In this way, the free radical becomes stable and won’t be able to damage any DNA or cellular structure hence stopping the undesirable effects on the skin.
Vitamin C fights against the effect of both UVB (wavelength: 290 – 320 nanometres) which mostly effects the external layers of the ski and UVA (wavelength: 320 – 400 nanometres), which are the most dangerous as they can penetrate deep into the skin cell, mutating the DNA molecule, altering and destroying collagen, elastin and other skin cellular structures. As UVA can penetrate 30 – 40 times deeper than UVB it is responsible for causing skin aging, hyper pigmentation. On the contrary, UVB is mostly related to sun burn, production of free radicals and skin cancer. The use of a properly-applied sun cream can only stop around 55% of free radicals produced by UV rays. The 45% of free radicals left, responsible for photo-aging can be blocked by the application of the powerful antioxidant vitamin C. Vitamin C doesn’t create a protective shield against the UV rays, since it doesn’t absorb them, instead it neutralizes the dangerous free radicals. This highly beneficial and desirable effect cannot be provided by any solar cream. That’s why it’s so important to use both solar cream and vitamin C serum for best protection.
From dermatological studies (3) it has been demonstrated that when vitamin C works synergistically with vitamin E; the combination of the two vitamins gives the best protection against the major factors which cause aging, such as environmental elements. Vitamin C in conjunction with vitamin E protects significantly the skin cell structure avoiding premature aging and hyper-pigmentation.
Our formulation of Stay-C 50 has been proven to inhibit the hyper-synthesis of melanin, which is responsible for hyper-pigmentation. Doing so, Stay-C 50 acts as an effective skin brightener, treating age and dark spots, bringing out a lustrous, translucent complexion, a more even tone and significantly reducing dark spots and freckles. Stay-C 50 has also been recognised to be less irritating than the normal Vitamin C, being gentler on the skin.
The combination of Ferulic Acid, Vitamin C and E which are all found inside Kleem Organics Vitamin C serum increases its efficacy 8 times more compared to any other serum, also helping to prevent also skin cancer.
The high 20% concentration of Vitamin C Stay-C 50 inside the serum allows the vitamin C to stimulate and boost the collagen production, molecules of which are the building blocks of our skin, in two different ways. Firstly it acts as the co-factor for the pre-collagen molecules. When vitamin C is absorbed inside the skin cells it attracts these two pre-collagen molecules forming the well- known collagen. Secondly it indirectly stimulates the gene responsible for the production of collagen.


Clinically speaking, the efficacy of the vitamin C serum obviously depends on the formulation and stability of vitamin C, but is also proportional to its concentration which cannot be more than 20%. The half-life (or half the time it remains effective) after achieving maximum concentration in the skin is 4 days. As the vitamin C level in the skin decreases with the higher exposure to the UV rays it would be highly recommendable to apply vitamin C serum twice a day (ideally every 8 hours for intense sun exposure), once in the morning for an adequate photo-protection and once before bed time for skin care repair.
Stay-C 50 vitamin C serum has been tested to be the most physiologically-effective serum which is delivered into the dermis in an adequate quantity for the highest UV protection preventing premature aging and hyper pigmentation.